ANALYZING THE POTENTIAL BIOLOGICAL DETERMINANTS OF AUTISM SPECTRUM DISORDER: FROM NEUROINFLAMMATION TO THE KYNURENINE PATHWAY

Analyzing the Potential Biological Determinants of Autism Spectrum Disorder: From Neuroinflammation to the Kynurenine Pathway

Autism Spectrum Disorder (ASD) etiopathogenesis is still unclear and no effective preventive and treatment measures have been identified.Research has focused on the potential role of neuroinflammation and the Kynurenine pathway; here we review the nature of these interactions.Pre-natal or neonatal infections would induce microglial activation, with

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Redox signaling modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule-regulating proteins

Many life processes are 153 regulated by physiological redox signaling, but excessive oxidative stress can damage biomolecules and contribute to disease.Neuronal microtubules are critically involved in axon homeostasis, regulation of axonal transport, and neurodegenerative processes.However, whether and how physiological redox signaling affects axo

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FEATURES OF THE LEGAL STATUS OF CONVICTS TO PUNISHMENTS THAT ARE NOT ASSOCIATED WITH ISOLATION FROM SOCIETY, ASSOCIATED WITH THE FORCED INVOLVEMENT OF THE CONVICTED PERSON IN LABOR

The relevance of the research issues lies in the fact that the criminal policy of our state is aimed at expanding the possibility of imposing punishments that are not associated with isolation from society, associated with the forced involvement of a convicted 153 person to work.The purpose of the study is to analyze criminal, penal enforcement and

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